I may have entered Argentina by plane, but my departure via the scenic bus ride from Mendoza to Santiago (Chile) was worth the extra transit time.
In Mendoza, I bought my bus ticket from Andesmar a few days in advance for just $36.
By comparison, flights cost several hundred dollars, and you miss some of the most beautiful landscapes outside of Patagonia.
The bus ride from Mendoza to Santiago lasted about seven hours, including the time it took to pass through Argentina and Chilean Immigration.
The highway passes by Puenta del Inca, but this natural geologic bridge can't be viewed from the bus. My photo in this article was taken a few days earlier on a separate tour.
Another point of interest you can see from the bus, if only for a few seconds, is Aconcagua, South America's tallest mountain at 22,837 feet (6,960 meters).
I lucked out in that it was a beautiful, clear day. Thanks to the GPS on my iPhone, I snapped a photo of the cloud-shrouded peak as we passed it by.
Dave is the Founder and Editor in Chief of Go Backpacking and Feastio. He's been to 66 countries and lived in Colombia and Peru. Read the full story of how he became a travel blogger.
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Thursday 24th of November 2016
Hi, I shall be in Medellin between Dec. 16, and leaving at 19. Any tips for Medellin. After Medellin, I shall travel south to Brazil, Uruguay, Argentina, and last to Chile before flying back to Toronto. Your advice will be greatly appreciated. Stephen
Sunday 26th of June 2016
I'm planning to catch the bus from Santiago to Mendoza in November and on the return journey, need to be back in Santiago by Friday, 25th November to catch the flight home. I have been told that the bus schedule isn't published until 4-6 weeks before departure. Do you know if generally there are buses on this route every day and are there any overnight buses?
Monday 27th of June 2016
I don't know.
Friday 10th of June 2016
Hi Dave! Would you know how the road is during winter? I've read somewhere that the roads partially close or something during winter. We will be doing a South America trip (Peru, Bolivia, Chile and Argentina) next month (July) and was also thinking about doing your Mendoza - Cordoba - Buenos Aires route. :)
Friday 10th of June 2016
I think the pass may be closed in Winter due to the amount of snow they get. It'd be quite dangerous. You'd probably have to fly.
Friday 16th of October 2015
We are thinking of doing the same route but the opposite direction, Santiago to Mendoza. Just curious, if there are no breaks other than the border crossing, is there a change of driver somewhere along the route? This trip is currently showing as 11.5 hours online, so rather a long haul for one driver.
Monday 3rd of August 2015
Hi Dave, Thank you for a great post! Slightly strange but practical question -- Can you let me know if there are any toilet break stops along the way! Also, do the windows open on the coach? :) Thanks
Wednesday 5th of August 2015
The only break I recall was when we were crossing the border. I believe snacks were served on the bus, and it was equipped with a bathroom, but I can't recall 100% for sure.